New Resource on the Search for Alternatives

Resources in Animal Alternatives is a recent addition to the UCLA Biomedical Library online resource series and is designed to serve as a starting point for locating information on any topic in the field of animal testing alternatives.

Zoonoses and Zoonotic Information

Information regarding occupational risks associated with zoonotic diseases is now available on the UCLA Health Protection Tracking System (HPTS) website. Zoonotic diseases are animal infections which, under certain circumstances, are communicable to humans. All animal users are encouraged to review this information and follow the safety guidelines when working with laboratory animals.

Regulatory Update: Recent News of the Rats, Mice, and Birds Issue; Electronic Gateway to Enhance Public Participation in Federal Rulemaking

Regulations.gov is the U.S. Government website that makes it easier for you to participate in Federal rulemaking. On this site, you can find, review, and submit comments on Federal documents that are open for comment and published in the Federal Register. Participating government agencies include the US Department of Agriculture (USDA), Department of Health and Human Services (DHHS), and the … Read More

ARC Policy on Toe-Clipping

In order to comply with the recommendations of the Guide for the Care and Use of Laboratory Animals, the ARC has issued a policy prohibiting the practice of toe-clipping as a means of identifying rodents unless explicit approval is obtained from the ARC. For additional details, please refer to the ARC Policy on Toe-Clipping for Animal Identification.

The Literature Search for Alternatives

In conducting literature searches for alternatives (i.e., refinement, reduction, replacement), investigators are encouraged to utilize the following resources for guidance: A Guide to Searching for Alternatives for the Use of Laboratory Animals How to Search for Alternatives Tips for Searching for Alternatives to Animal Research and Testing The Search for Alternatives

NIH Announcements Regarding Just-In-Time for IACUC Review, Use of Carbon Dioxide for Euthanasia of Small Animals, and Research with Recombinant DNA Molecules

NIH Announces Just-In-Time for IACUC Review The National Institutes of Health (NIH) is amending the PHS Policy on Humane Care and Use of Laboratory Animals (PHS Policy) to allow “just-in-time” submission of IACUC approval. As of September 1, 2002, verification of IACUC approval for competing applications may be submitted at any time subsequent to peer review but prior to award, … Read More

Important Notice Regarding the 2000 Report of the AVMA Panel on Euthanasia

The PHS Policy on Humane Care and Use of Laboratory Animals requires that Institutional Animal Care and Use Committees (IACUCs) determine that the methods of euthanasia used will be consistent with the recommendations of the American Veterinary Medical Association (AVMA) Panel on Euthanasia, unless a deviation is justified for scientific reasons in writing by the investigator. In addition, USDA Animal … Read More

Standard Operating Procedure Governing Facilities for Mice at UCLA

On July 2, 2001, the Vice Chancellor for Research issued a notice to introduce the Standard Operating Procedure (SOP) Governing Facilities for Mice at UCLA. All personnel who work in these facilities are expected to review and follow these procedures in order to avoid cross-contamination between facilities, minimize the spread of infection within facilities, and ensure the maintenance of pathogen-free … Read More