The concept of the three Rs was originally described in the book, The Principles of Humane Experimental Technique (1959), by Russell and Burch. The 3Rs are reduction in the number of animals used, refinement of techniques and procedures to reduce pain or distress, and replacement of animals with non-animal techniques or use of less-sentient species.
Intent of Grant: The aim of the program is to promote and support pilot studies designed to investigate refinement of methods, and/or reduction and replacement of animals, as described above.
Amount of Grant: Up to $20,000 awarded twice annually. This funding opportunity is provided by the Office of the Vice Chancellor for Research.
Requirements for Submission: Applications can be submitted using the online 3R Grant Proposal Form. The proposal should contain:
- A succinct and accurate description of the proposed work (experimental design and methods),
- The objective and specific aims,
- A clear description of the relatedness to the goals of reduction, refinement and replacement of animal use in research, and
- A short budget.
Please note that the proposal should not exceed 7500 characters.
Criteria for Award: A sub-committee of the ARC will evaluate applications with regard to scientific merit, budget appropriateness, and relatedness to 3Rs. Awards will be assigned a priority score based on the scoring system used by the NIH. Please note that ARC review and approval of the proposed animal work will be required prior to initiating experiments.
Page Last Updated: August 3, 2023